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08097nam a2201021 i 4500 |
| 001 - CONTROL NUMBER |
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EBC3563988 |
| 003 - CONTROL NUMBER IDENTIFIER |
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MiAaPQ |
| 006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION |
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m o d | |
| 007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION |
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cr cnu|||||||| |
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150709s2015 nyua foab 001 0 eng d |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| International Standard Book Number |
9781606506707 |
| Qualifying information |
electronic |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
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| Cancelled/invalid ISBN |
9781606506677 |
| Qualifying information |
print |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
(MiAaPQ)EBC3563988 |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
(Au-PeEL)EBL3563988 |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
(CaPaEBR)ebr11071696 |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
(CaONFJC)MIL801563 |
| 035 ## - SYSTEM CONTROL NUMBER |
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| System control number |
(OCoLC)913604543 |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
FINmELB |
| Language of cataloging |
spa |
| Description conventions |
rda |
| Transcribing agency |
FINmELB |
| 050 #4 - LIBRARY OF CONGRESS CALL NUMBER |
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| Classification number |
QP624.5.D726 |
| Item number |
S526 2015 |
| 082 0# - DEWEY DECIMAL CLASSIFICATION NUMBER |
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| Classification number |
572.8636 |
| Edition number |
23 |
| 100 1# - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Sharma, Kal Renganathan., |
| Relator term |
author. |
| 245 10 - TITLE STATEMENT |
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| Title |
Microarray analysis : |
| Remainder of title |
biochips and eradication of all diseases / |
| Statement of responsibility, etc |
Kal Renganathan Sharma. |
| 264 #1 - |
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| -- |
New York, [New York] (222 East 46th Street, New York, NY 10017) : |
| -- |
Momentum Press, |
| -- |
2015. |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
1 online resource (xxviii, 295 pages) : |
| Other physical details |
illustrations. |
| 336 ## - |
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text |
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rdacontent |
| 337 ## - |
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computer |
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rdamedia |
| 338 ## - |
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online resource |
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rdacarrier |
| 490 1# - SERIES STATEMENT |
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| Series statement |
Biomedical engineering collection |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc |
Includes bibliographical references (pages 271-282) and index. |
| 505 0# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
1. Genominomics and prospects -- Chapter objectives -- Human genome project completed -- Biochips -- Next-generation sequencing -- Applications of biochips -- Consanguinous marriages -- Ashkenazi Jews -- Cystic fibrosis -- Tuberculosis -- Cancer -- Sickle-cell anemia -- Small pox -- Paleo genomes -- Colony collapse disorder -- Schizophrenia -- Prenatal testing -- DNA for forensic investigation -- Genomic surveillance -- Bio-corrosion -- Human immunodeficiency syndrome -- Microarray analysis -- Pioneers in double-helix structure of DNA -- Genominomics, economics of sequencing, $1,000 -- Genome is within reach -- Genetically modified crops -- Glossary -- Summary -- |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
2. Microarray analysis -- Chapter objectives -- Molecular basis for disease -- Microarray technology development -- Specifications -- Nanoprint microarrayer -- Ten tips for five-step process -- Step 1 formulation of a biologic question -- Step 2 sample preparation -- Step 3 biochemical reaction -- Step 4 microarray detection -- Step 5 microarray data analysis and modeling -- Microarray fluorescence detection -- Confocal scanning microscope -- Quality of substrate surface -- Phosphoramadite synthesis -- Summary -- |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
3. Sequencing technology advances -- Chapter objectives -- Genomes completed -- Next-generation sequencers -- Gene mapping -- Electrophoretic methods -- Microfluidic separations -- Polymer liquids -- Transport parameters -- Transient concentration profile predicted using the a capite ad calcem concentration non-Fick diffusion equation in a semi-infinite medium -- Convection and diffusion -- Summary -- |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
4. Applications -- Chapter objectives -- Cancer -- Kinetic model for progression of cancer -- Proteomics and Michaelis and Menten kinetics -- Immune action mechanism -- DNA hybridization kinetics-diffusion effects -- Gene modifications -- DNA-melting temperature -- Genetic disorders and microarray analysis -- Tissue microarrays and cell microarrays -- Bio-based polymers -- Gene silencing -- Metabolomics -- Recombinant DNA technology and genetically -- Modified crops -- Biodiesel -- Consecutive-competitive reactions -- Centrifugal separation of fame and glycerol: torque requirements -- Shear flow theory -- Results -- Gene therapy -- Gene activity in songbirds similar to humans -- Glossary -- Summary -- |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
5. Next-generation sequencing -- Chapter objectives -- Blotting techniques -- Sanger sequencing -- Sequencing by synthesis -- Sequencing by ligation -- Pyrosequencing -- Single-molecule sequencing -- DNA sequencing through nanopore -- Glossary -- Summary -- |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
6. Biochip manufacturing -- Chapter objectives -- Three approaches -- Ex situ manufacturing -- Commercial instruments -- Time to print -- Summary -- |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
7. Statistical characterization and normalization -- Chapter objectives -- Housekeeping genes and normalization -- Clustering -- Supervised -- Variation filter -- Unsupervised -- Pearson's correlation coefficient -- Principal component analysis -- Cluster determination -- Nearest neighbor clustering -- Unsupervised classification -- Silhouette method -- Dunn's validation index -- Davies-Bouldin index -- C-index -- Self-organizing maps -- K-means clustering -- Agglomerative clustering -- Dendrograms -- Two-dimensional dendrograms -- Division or partition clustering -- Bayesian clustering -- Boolean networks -- Bayesian networks -- Relevance networks -- Glossary -- Summary -- |
| 505 8# - FORMATTED CONTENTS NOTE |
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| Formatted contents note |
References -- About the author -- Index. |
| 506 1# - RESTRICTIONS ON ACCESS NOTE |
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| Terms governing access |
Restricted to libraries which purchase an unrestricted PDF download via an IP. |
| 520 3# - SUMMARY, ETC. |
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| Summary, etc |
Microarray Analysis is a natural outgrowth of the author's teaching and research into the field of microarray processing, a fast growing and developing field. The book highlights the development of various microarray analysis tools and the applications of the technology towards disease prevention and eradication. The goal is to illustrate the many sequencing methods in place, and to show the various applications of these methods. This book will show how the biochemical reactions involved in the different steps of the cure process can be studied using microarray methods. Examples will be provided throughout the text of various disease states, including the spread of cystic fibrosis in children consanguineous marriages in Saudi Arabia, genetic disorders, and autoimmune disorders. The protocols from sample preparation to confocal scanning microscopy and detectors using photo multiplier tubes, biochip manufacturing methods, advances in sequencing methods, microfluids, electrophoretic methods are discussed in detail. The Polymerase chain reaction, a technique used to amplify and simultaneously quantify a targeted DNA molecule is explored. The criteria for choosing the best surface to use for microarray analysis is elloborated. Additionally, Microarray Analysis: Biochips and Eradication of Disease will feature the statistical methods needed for analysis of DNA data from microarray analysis, including shotgun and next generation sequencing. |
| 588 ## - |
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| -- |
Title from PDF title page (viewed on July 9, 2015). |
| 650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM |
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| Topical term or geographic name as entry element |
DNA microarrays. |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Genominomics |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Next Generation Sequencing |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Microarray Analysis |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Cancer Treatment |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Cancer Progression |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Gene Silencing |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Single Nucleotide Polymorphism |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Genetic Disorders |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Autoimmune Disorders |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Genetically Modified Crops |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Small Pox |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Molecular Basis for Disease |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Biochemical Reactions |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Multiple Reactions |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Confocal Scanners |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Phosphoramidites |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Electrophoretic Methods |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Microfluidic Separations |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Gene Mapping |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Polymer Liquids |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Relaxation Phenomena |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Gene Modifications |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Splicing |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Genomics |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Proteomics |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Metabolomics |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
J. Curcas |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Biodiesel |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Blotting |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Sanger Sequencing |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Sequencing by Synthesis |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Sequencing by Ligation |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Pyrosequencing |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Single Molecule Sequencing |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Nanopore |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Biochip Manufacturing |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
House Keeping Genes |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Clustering |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
k means Clustering |
| 653 ## - INDEX TERM--UNCONTROLLED |
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| Uncontrolled term |
Baysean Networks |
| 655 #4 - INDEX TERM--GENRE/FORM |
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| Genre/form data or focus term |
Libros electronicos. |
| 776 08 - ADDITIONAL PHYSICAL FORM ENTRY |
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| Display text |
Print version: |
| International Standard Book Number |
9781606506677 |
| 830 #0 - SERIES ADDED ENTRY--UNIFORM TITLE |
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| Uniform title |
Biomedical engineering collection. |
| 856 40 - ELECTRONIC LOCATION AND ACCESS |
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| Uniform Resource Identifier |
<a href="https://ebookcentral.proquest.com/lib/bcsl-ebooks/detail.action?docID=3563988">https://ebookcentral.proquest.com/lib/bcsl-ebooks/detail.action?docID=3563988</a> |
| Public note |
Click to View |